Hyperion (computer), an early portable computer
Hyperion Entertainment, a computer game producer
Hyperion Solutions, a business software company owned by Oracle
Hyperion, a RuneScape Emulator by Graham Edgecombe
Hyperion, an IRC daemon previously used by the Freenode IRC network

Hyperion (tree), the name of a coast redwood (Sequoia sempervirens) in Northern California that was measured at 115.61 metres (379.3 ft), which ranks it as the world’s tallest known living tree
Hyperion (yacht), the name of a 155.5-foot sailing yacht built by the Royal Huisman in the Netherlands in 1998 and designed by German Frers
Hyperion , a genus of beetles in the Carabidae family
HMS Hyperion, the name of several Royal Navy ships
Hyperion Pictures, a film production company
Hyperion Power Generation, a nuclear power company
Hyperion Records, a record label